Название
Anti-pan Cytokeratin antibody [AE1/AE3 + 5D3]
Applications
IHC-P, ICC/IF, Flow Cyt
Immunogen
Full Length Protein corresponding to Human KRT8. The exact immunogen used to generate this antibody is proprietary information. P05787
Подтвержденная реактивность
Human, Chicken, Pig, Goat, Dog
Специфичность
The ab86734 is a combination of [AE1/AE3] and [5D3] clones and can be used to detect most human epithelia. [AE1/AE3] recognizes acidic and basic subfamilies of cytokeratins, with molecular weights ranging from 40 to 67 kDa. [5D3] recognizes Cytokeratin 8 and 18 intermediate filament proteins. In normal tissues, [5D3] recognizes all simple and glandular epithelium. It has been observed that [AE1/AE3] has had problems marking certain tissues types and adenocarcinomas. The addition of [5D3] may remedy some of the limitations observed when staining with [AE1/AE3] alone.